severe diarrhea with glp 1 GLP-1s are notorious for their side effects. The main thing they're known for these days — weight loss — is actually a side effect. It's not just weight loss, though. GLP-1s are Weeks of Debilitating Symptoms': Mayim

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R., Lower Activity of Superoxide Dismutase and High Activity of Glutathione Reductase in Erythrocytes From Centenarians, Age and Ageing, 1998

However, real-world data from the Cleveland Clinic found that a substantial share of patients maintained meaningful loss at one year, largely through restarting or transitioning treatment